BA/OneWorld Best routing London to CLE (Cleveland Hopkins).

Just wondered if any of the wise folk on here had suggestions for the best routing.
BA website offers me Lon JFK CLE and Lon ORD CLE - both both use regional airlines which I prefer to avoid if a mainline alternative is available.
Any thoughts? (Obviously, I'd prefer OneWorld alliance airlines to get Avios and Tier points).
BA website offers me Lon JFK CLE and Lon ORD CLE - both both use regional airlines which I prefer to avoid if a mainline alternative is available.
Any thoughts? (Obviously, I'd prefer OneWorld alliance airlines to get Avios and Tier points).