Hello hello,
Last row PE on the A333 are fair seats. There are bulkheads behind the last row so don't worry about being kicked in the back by Economy.
Advantages are that with no one behind you there will be no prodding at the VERA Touch IFE interface which can get a bit annoying when people are effectively hitting the back of your seat constantly. You also have the ability to fully recline without worrying about annoying the pax behind... bothers some people but not all.
Disadvantage is that you are the last to chose the meal so they may have run out of your first choice by the time the trolleys come down... hopefully not though.
Have a good flight 8D